abstract：:Background: Despite advances in behavioral and pharmacotherapy interventions, substance use disorders (SUDs) are frequently refractory to treatment. Glutamatergic dysregulation has received increasing attention as one common neuropathology across multiple substances of abuse. Ketamine is a potent N-methyl-D-aspartate ...

journal_title：Frontiers in psychiatry

authors： Jones JL,Mateus CF,Malcolm RJ,Brady KT,Back SE

更新日期：2018-07-24 00:00:00

abstract：:Objective: Patients with schizophrenia exhibit impaired social cognition, especially in the recognition and expression of facial emotions, aspects of communication profoundly interlinked in an embodied approach of cognition. Nevertheless, many training programs have been developed that focus on either of these deficit...

journal_title：Frontiers in psychiatry

authors： Sevos J,Grosselin A,Gauthier M,Carmona F,Gay A,Massoubre C

更新日期：2018-07-23 00:00:00

abstract：:Patients with cancer are more likely to develop depression than the general population, which negatively impacts their quality of life and prognosis. In order to identify effective antidepressants catered toward cancer patients, the biology of depression in the context of cancer must be well-understood. Many theories ...

journal_title：Frontiers in psychiatry

authors： Young K,Singh G

更新日期：2018-07-10 00:00:00

abstract：:Objectives: While evidence that episodes of mania in bipolar I are associated with changes in bioenergetic and regional cerebral blood flow (rCBF) and cerebral blood flow velocity (rCBFV), both the regions and the extent of these changes have not yet been defined. Therefore, we determined the pattern of regional cereb...

journal_title：Frontiers in psychiatry

authors： Wang Y,Liu X,Li P,Zhou H,Yang L,Zheng L,Xie P,Li L,Liao DJ,Liu Q,Fang D

更新日期：2018-07-04 00:00:00

abstract：:Marijuana is the most commonly used drug of abuse among adolescents. Considerable clinical evidence supports the hypothesis that adolescent neurodevelopmental exposure to high levels of the principal psychoactive component in marijuana, -delta-9-tetrahydrocanabinol (THC), is associated with a high risk of developing p...

journal_title：Frontiers in psychiatry

authors： Renard J,Rushlow WJ,Laviolette SR

更新日期：2018-07-02 00:00:00

abstract：:Background: Insufficient sleep is common in daily life and can lead to cognitive impairment. Sleep disturbance also exists in neuropsychiatric diseases. However, whether and how acute and chronic sleep loss affect brain morphology remain largely unknown. Methods: We used voxel-based morphology method to study the brai...

journal_title：Frontiers in psychiatry

authors： Dai XJ,Jiang J,Zhang Z,Nie X,Liu BX,Pei L,Gong H,Hu J,Lu G,Zhan Y

更新日期：2018-06-27 00:00:00

abstract：:Background: Attenuated positive psychotic symptoms represent the defining features of the clinical high-risk for psychosis (CHR-P) criteria. The effectiveness of each available treatment for reducing attenuated positive psychotic symptoms remains undetermined. This network meta-analysis (NMA) investigates the consiste...

journal_title：Frontiers in psychiatry

authors： Davies C,Radua J,Cipriani A,Stahl D,Provenzani U,McGuire P,Fusar-Poli P

更新日期：2018-06-12 00:00:00

abstract：:Major depression is a high-prevalence mental disease with major socio-economic impact, for both the direct and the indirect costs. Major depression symptoms can be faked or exaggerated in order to obtain economic compensation from insurance companies. Critically, depression is potentially easily malingered, as the sym...

journal_title：Frontiers in psychiatry

authors： Monaro M,Toncini A,Ferracuti S,Tessari G,Vaccaro MG,De Fazio P,Pigato G,Meneghel T,Scarpazza C,Sartori G

更新日期：2018-06-08 00:00:00

abstract：:Patients with severe mental disorders die on average 20 years prior to the general population. This mortality gap is mainly due to the higher prevalence of physical diseases and the adoption of unhealthy lifestyle behaviors.The LIFESTYLE trial aims to evaluate the efficacy of a new psychosocial group intervention (inc...

journal_title：Frontiers in psychiatry

authors： Sampogna G,Fiorillo A,Luciano M,Del Vecchio V,Steardo L Jr,Pocai B,Barone M,Amore M,Pacitti F,Dell'Osso L,Di Lorenzo G,Maj M,LIFESTYLE Working Group.

更新日期：2018-06-07 00:00:00

abstract：:This study explored how different forms of reward-based decision-making are associated with pathological gambling (PG) among abstinent individuals with prior dependence on different classes of drugs. Participants had lifetime histories of either "pure" heroin dependence (n = 64), "pure" amphetamine dependence (n = 51)...

journal_title：Frontiers in psychiatry

authors： Wilson MJ,Vassileva J

更新日期：2018-06-05 00:00:00

abstract：:Magnetic seizure therapy (MST) is a potential alternative to electroconvulsive therapy (ECT), but there is currently a lack of reports about MST in Chinese patients with schizophrenia. Our objective was to investigate the feasibility and acceptability of add-on MST in the treatment of patients with schizophrenia. Eigh...

journal_title：Frontiers in psychiatry

authors： Jiang J,Li Q,Sheng J,Yang F,Cao X,Zhang T,Jia Y,Wang J,Li C

更新日期：2018-05-29 00:00:00

abstract：:Refugee children share a large number of pre-, peri-, and post-migration risk factors, which make them vulnerable for developing mental health concerns. Within the last few years, a large number of families with young children have sought refuge in Germany. However, children's mental health status in Germany is mostly...

journal_title：Frontiers in psychiatry

authors： Buchmüller T,Lembcke H,Busch J,Kumsta R,Leyendecker B

更新日期：2018-05-25 00:00:00

abstract：:Introduction: Antipsychotic treatment can improve the symptoms of schizophrenia; however, residual symptoms after antipsychotic treatment are frequent. The effects of exercise on the symptoms of schizophrenic patients under antipsychotic treatment are inconclusive. The aim of this randomized case-control study was to ...

journal_title：Frontiers in psychiatry

authors： Wang PW,Lin HC,Su CY,Chen MD,Lin KC,Ko CH,Yen CF

更新日期：2018-05-15 00:00:00

abstract：:As the population ages and the number of people living with dementia or mild cognitive impairment (MCI) continues to increase, it is critical to identify creative and innovative ways to support and improve their quality of life. Motion-based technology has shown significant potential for people living with dementia or...

journal_title：Frontiers in psychiatry

authors： Astell AJ,Czarnuch S,Dove E

更新日期：2018-05-11 00:00:00

abstract：:Social cognition has become recognized as an important driver of functional outcomes and overall recovery in patients with schizophrenia, mediating the relationship between neurocognition and social functioning. Since antipsychotic therapy targeting remission of clinical symptoms has been shown to have a limited impac...

journal_title：Frontiers in psychiatry

authors： Javed A,Charles A

更新日期：2018-04-24 00:00:00

abstract：Introduction:The Bermond-Vorst Alexithymia Questionnaire (BVAQ) has been validated in student samples and small clinical samples, but not in the general population; thus, representative general-population norms are lacking. Aim:We examined the factor structure of the BVAQ in Longitudinal Internet Studies for the Socia...

journal_title：Frontiers in psychiatry

authors： de Vroege L,Emons WHM,Sijtsma K,van der Feltz-Cornelis CM

更新日期：2018-04-23 00:00:00

abstract：:Studies utilizing functional magnetic resonance imaging (fMRI) cue-reactivity paradigms have demonstrated that short-term abstinent or current methamphetamine (MA) users have increased brain activity in the ventral striatum, caudate nucleus and medial frontal cortex, when exposed to MA-related visual cues. However, pa...

journal_title：Frontiers in psychiatry

authors： Huang S,Zhang Z,Dai Y,Zhang C,Yang C,Fan L,Liu J,Hao W,Chen H

更新日期：2018-04-19 00:00:00

abstract：Background:Prepulse inhibition (PPI) of the acoustic startle reflex is an operational measure of sensorimotor gating. The findings on PPI deficits in bipolar disorder (BD) are inconsistent among studies due to various confounding factors such as gender. This study aimed to assess sensorimotor gating deficits in patient...

journal_title：Frontiers in psychiatry

authors： Matsuo J,Ota M,Hidese S,Teraishi T,Hori H,Ishida I,Hiraishi M,Kunugi H

更新日期：2018-04-18 00:00:00

abstract：Objectives:Deviations from typical word use have been previously reported in clinical depression, but language patterns of mild depression (MD), as distinct from normal sadness (NS) and euthymic state, are unknown. In this study, we aimed to apply the linguistic approach as an additional diagnostic key for understandin...

journal_title：Frontiers in psychiatry

authors： Smirnova D,Cumming P,Sloeva E,Kuvshinova N,Romanov D,Nosachev G

更新日期：2018-04-10 00:00:00

abstract：Introduction:Visual impairment (VI) is associated with a variety of comorbidities including physical and mental health in industrial countries. Our aim is to examine associations between self-reported impairment and depressive symptoms in the German population. Methods:The point prevalence of self-reported VI in Germa...

journal_title：Frontiers in psychiatry

authors： Schuster AK,Tesarz J,Rezapour J,Beutel ME,Bertram B,Pfeiffer N

更新日期：2018-04-09 00:00:00

abstract：Background:Loss aversion is a central and well operationalized trait behavior that describes the tendency for humans to strongly prefer avoiding losses to making equivalent gains. Human decision-making is thus biased toward safer choices. Aim:The aim of this study was to explore the relationship between loss aversion ...

journal_title：Frontiers in psychiatry

authors： Hadlaczky G,Hökby S,Mkrtchian A,Wasserman D,Balazs J,Machín N,Sarchiapone M,Sisask M,Carli V

更新日期：2018-04-05 00:00:00

abstract：Background:Among Muslim patients, a common cultural concept of distress is the notion that jinn may be the cause of mental health problems, especially in the presence of hallucinations. Objective:This study examines the frequency with which this attribution style is manifest in a specific psychiatric outpatient popula...

journal_title：Frontiers in psychiatry

authors： Lim A,Hoek HW,Ghane S,Deen M,Blom JD

更新日期：2018-03-28 00:00:00

abstract：:As established in a wealth of studies subtle motor and sensory neurological abnormalities or neurological soft signs (NSS) are frequently found in patients with schizophrenia at any stage of their illness. However, the potential impact of chronicity and age on NSS was scarcely investigated. Therefore, we assessed NSS ...

journal_title：Frontiers in psychiatry

authors： Herold CJ,Lässer MM,Seidl UW,Hirjak D,Thomann PA,Schröder J

更新日期：2018-03-26 00:00:00

abstract：Background:Disorganization of semantic memory in patients with schizophrenia has been studied by referring to their category fluency performance. Recently, data-mining techniques such as singular value decomposition (SVD) analysis have been reported to be effective in elucidating the latent semantic memory structure in...

journal_title：Frontiers in psychiatry

authors： Sumiyoshi C,Fujino H,Sumiyoshi T,Yasuda Y,Yamamori H,Fujimoto M,Hashimoto R

更新日期：2018-03-21 00:00:00

abstract：Background:Anorexia nervosa (AN) is characterized by severe malnutrition as well as inefficiencies in neurocognitive functioning, which are believed to contribute to the maintenance of disordered eating. The aim of this study was to examine the impact of individual cognitive remediation therapy (CRT) on neurocognition ...

journal_title：Frontiers in psychiatry

authors： Leppanen J,Adamson J,Tchanturia K

更新日期：2018-03-20 00:00:00

abstract：Background:Past studies using the Bonn Scale for the Assessment of Basic Symptoms (hereafter, Bonn Scale) have shown that self-reported perceptual/cognitive disturbances reveal which persons have or will soon develop schizophrenia. Here, we focused specifically on the clinical value of self-reported visual perceptual a...

journal_title：Frontiers in psychiatry

authors： Keane BP,Cruz LN,Paterno D,Silverstein SM

更新日期：2018-03-12 00:00:00

abstract：:Glutamate is involved in excitatory neurotransmission and metabolic processes related to brain function. Previous studies using proton functional magnetic resonance spectroscopy (1H fMRS) have demonstrated elevated cortical glutamate levels by 2-4% during visual and motor stimulation, relative to periods of no stimula...

journal_title：Frontiers in psychiatry

authors： Woodcock EA,Anand C,Khatib D,Diwadkar VA,Stanley JA

更新日期：2018-03-06 00:00:00

abstract：:Naphthalen-1-yl-(1-pentylindol-3-yl)methanone (JWH-018) is a synthetic compound found in psychoactive "spice" products that activates cannabinoid receptors. Preclinical evidence suggests that exposure to synthetic cannabinoids increases 5-HT2A/2C receptor function in the brain, an effect which might contribute to psyc...

journal_title：Frontiers in psychiatry

authors： Elmore JS,Baumann MH

更新日期：2018-02-27 00:00:00

abstract：:We use auditory verbal hallucinations (AVH) to illustrate the challenges in defining and assessing target engagement in the context of transcranial direct current stimulation (tDCS) for psychiatric disorders. We defined the target network as the cluster of regions of interest (ROIs) that are consistently implicated in...

journal_title：Frontiers in psychiatry

authors： Lee WH,Kennedy NI,Bikson M,Frangou S

更新日期：2018-02-22 00:00:00

abstract：Background:Epidemiologic evidence highlights the harmful consequences of unemployment on health and well-being. This emphasizes the need to design low-cost interventions to prevent the adverse mental health effects of unemployment. The main aim of this study was to create expert-consensus regarding development and impl...

journal_title：Frontiers in psychiatry

authors： Santos O,Lopes E,Virgolino A,Stefanovska-Petkovska M,Dinis A,Ambrósio S,Heitor MJ

更新日期：2018-02-07 00:00:00

abstract：:In clinical settings, nitrous oxide gas is a safe anesthetic used during childbirth, in dentistry, and to relieve anxiety in emergencies. Colloquially known as "hippy crack"' or "laughing gas," it is increasingly taken recreationally for its euphoric and relaxing effects and hallucinogenic properties. Using a self-rep...

journal_title：Frontiers in psychiatry

authors： Ehirim EM,Naughton DP,Petróczi A

更新日期：2018-01-22 00:00:00

abstract：Objective:There is a growing interest in evaluating the effectiveness of compassion interventions for treating psychological disorders. The present study evaluated the effectiveness of "attachment-based compassion therapy" (ABCT) in the treatment of fibromyalgia (FM), and the role of psychological flexibility as a medi...

journal_title：Frontiers in psychiatry

authors： Montero-Marín J,Navarro-Gil M,Puebla-Guedea M,Luciano JV,Van Gordon W,Shonin E,García-Campayo J

更新日期：2018-01-16 00:00:00

abstract：:Task-based connectivity studies facilitate the understanding of how the brain functions during cognition, which is commonly impaired in schizophrenia (SZ). Our aim was to investigate functional connectivity during a working memory task in SZ. We hypothesized that the task-negative (default mode) network and the cognit...

journal_title：Frontiers in psychiatry

authors： Godwin D,Ji A,Kandala S,Mamah D

更新日期：2017-12-22 00:00:00

abstract：:Following the severe attacks by the so-called "Islamic State of Iraq and Syria" on the Yazidi population, which started in summer 2014, the state government of Baden-Württemberg, Germany, funded a Special-Quota Project to bring 1,000 very ill or left-behind women and children who were being held hostage to 22 cities a...

journal_title：Frontiers in psychiatry

authors： Gerdau I,Kizilhan JI,Noll-Hussong M

更新日期：2017-12-13 00:00:00

abstract：:Social sharing capacities have attracted attention from a number of fields of social cognition and have been variously defined and analyzed in numerous studies. Social sharing consists in the subjective awareness that aspects of the self's experience are held in common with other individuals. The definition of social ...

journal_title：Frontiers in psychiatry

authors： Colle L,Pellecchia G,Moroni F,Carcione A,Nicolò G,Semerari A,Procacci M

更新日期：2017-12-04 00:00:00

abstract：Background:Attentional dysfunctions constitute core cognitive symptoms in schizophrenia, but the precise underlying neurocognitive mechanisms remain to be elucidated. Methods:In this randomized, double-blind, sham-controlled study, we applied, for the first time, a theoretically grounded modeling approach based on Bun...

journal_title：Frontiers in psychiatry

authors： Gögler N,Papazova I,Oviedo-Salcedo T,Filipova N,Strube W,Funk J,Müller HJ,Finke K,Hasan A

更新日期：2017-11-29 00:00:00

abstract：:Depression has been associated with peripheral inflammatory processes and alterations in cellular immunity. Growing evidence suggests that immunological alterations may neither be necessary nor sufficient to induce depression in general, but seem to be associated with specific features. Using baseline data from the Ou...

journal_title：Frontiers in psychiatry

authors： Euteneuer F,Dannehl K,Del Rey A,Engler H,Schedlowski M,Rief W

更新日期：2017-11-23 00:00:00

abstract：:Suicidality is highly prevalent in patients at clinical high risk (CHR) for psychosis. Childhood adversities and trauma are generally predictive of suicidality. However, the differential effects of adversity/trauma-domains and CHR-criteria, i.e., ultra-high risk and basic symptom criteria, on suicidality remain unclea...

journal_title：Frontiers in psychiatry

authors： Schmidt SJ,Schultze-Lutter F,Bendall S,Groth N,Michel C,Inderbitzin N,Schimmelmann BG,Hubl D,Nelson B

更新日期：2017-11-20 00:00:00

abstract：Objective:Schizophrenia poses a tremendous health, social, and economic burden upon patients and society, indicating current treatment options remain inadequate. Recent findings from several lines of evidence have pointed to the importance of immune system involvement in not only premorbid neurodevelopmental but also s...

journal_title：Frontiers in psychiatry

authors： De Picker LJ,Morrens M,Chance SA,Boche D

更新日期：2017-11-16 00:00:00

abstract：:Cocaine addiction is a widespread psychiatric condition still waiting for approved efficacious medications. Previous studies suggested that simultaneous activation of nociceptin opioid (NOP) and mu opioid (MOP) receptors could be a successful strategy to treat cocaine addiction, but the paucity of molecules co-activat...

journal_title：Frontiers in psychiatry

authors： Shen Q,Deng Y,Ciccocioppo R,Cannella N

更新日期：2017-11-13 00:00:00